Dermatopathology and Diagnostics

Dermatopathology comprises study of the microscopic morphology of skin segments. It reflects pathophysiologic changes happening at the microscopic level in the skin and its appendages. The complete sequencing of the human genome has steered in an era of medical advances and it is due to Human Genome Project (HGP) .that was previously unconceivable. Scientists are repeatedly discovering novel genetic and epigenetic machineries that are linked with human disease states and therapeutic responses. The capability to determine the primary defect in single-gene diseases, many of which are rare, has improved both analysis in symptomatic patients and risk estimate of future disease in asymptomatic individuals.