Organizing Committee Member
Guang-Yu Yang
Director of Anatomic and Surgical Pathology
Northwestern University
USA
Biography
Guang-Yu Yang is the Joseph C. Calandra Research Professor in Pathology and Toxicology, Director of Anatomic and Surgical Pathology, Director of Surgical/GI Pathology Fellowship Program, Department of Pathology at Northwestern University, USA. He completed his PhD from China Medical University, Molecular Pathology in 1992. He has published more that 100 research papers in various repute journals. His long-term objective of our research is to study molecular mechanism and chemoprevention of chronic inflammation-driven carcinogenesis.
Research Area
To develop a molecular mimicking model of ulcerative colitis-associated carcinogenesis in rodents, and further to elucidate the role of inflammation-caused and dietary iron-enhanced nitro-oxidative stress and inflammatory mediators in DNA damage, cell proliferation and inflammation-driven carcinogenesis; 2) to study the pathogenesis and molecular biomarkers of pancreatic carcinoma in genetically engineered mouse model and in human; and 3) to develop an efficient strategy on the prevention of chronic inflammation-driven carcinogenesis, particularly interested in dietary nutrients, antioxidants, green tea and inositol compounds and specifically targeted on colorectal, pancreatic, and liver carcinogenesis.